Early Rise in Serum VEGF and PDGF Levels Predisposes Patients With a Normal MBL2 Genotype to Restenosis After Eversion Endarterectomy
نویسندگان
چکیده
منابع مشابه
Early rise in serum VEGF and PDGF levels predisposes patients with a normal MBL2 genotype to restenosis after eversion endarterectomy.
BACKGROUND AND PURPOSE Recently we found that the incidence of restenosis after carotid endarterectomy was significantly higher in patients homozygous for the normal genotype of mannose-binding lectin (MBL2) than in with patients with MBL2 variant genotypes. Several growth factors are also known to contribute to restenosis. Therefore, we investigated whether early postoperative changes in serum...
متن کاملHigh rate of early restenosis after carotid eversion endarterectomy in homozygous carriers of the normal mannose-binding lectin genotype.
BACKGROUND AND PURPOSE Mannose-binding lectin (MBL) is thought to influence the pathophysiology of cardiovascular disease by decreasing the risk of advanced atherosclerosis and by contributing to enhanced ischemia reperfusion injury. Thus, we investigated the role of MBL in restenosis after eversion endarterectomy in patients with severe carotid atherosclerosis. METHODS In a prospective study...
متن کاملLow c1-inhibitor levels predict early restenosis after eversion carotid endarterectomy.
OBJECTIVE Homozygotes for the normal (A) allele of mannose-binding lectin (MBL2) gene have higher risks to develop an early restenosis after eversion carotid endarterectomy (CEA). Activation of the lectin pathway is regulated by C1-inhibitor (C1-INH). The objective of the present study was to determine the predictive value of C1-INH in restenosis after CEA. METHODS AND RESULTS C1-INH and MBL-...
متن کاملcomparison of blood flow velocity changes in posterior cerebral artery measured with transcranial doppler sonography in migraineurs with visual aura and normal persons after photostimulation
چکیده ندارد.
15 صفحه اولCarotid Endarterectomy: Eversion Technique
The aim of this article is to explain technique of eversion CEA (carotid endarterectomy), as well as to determine that eversion CEA is more effective than conventional CEA. Eversion CEA can be performed in two methods. When atherosclerotic process mostly involves common carotid artery, the procedure should start with common carotid transection, followed by eversion CEA in cranial and than in ca...
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ژورنال
عنوان ژورنال: Stroke
سال: 2007
ISSN: 0039-2499,1524-4628
DOI: 10.1161/strokeaha.106.475954